| The branching pattern of the mistletoe plant also is opposite. The plant requires direct sunlight for best development, which explains why it usually is found high in the crown of tall trees. Mistletoe may change from green to a greenish-yellow color during the winter months, but this is not an indication that the plant is unhealthy.|
The best indication of mistletoe infection is the presence of dense clusters of vegetation in the crown of host trees. The evergreen mistletoe plant is most easily recognized in the winter months when deciduous trees have dropped their leaves. Trees vary in their susceptibility to mistletoe with water oak, sugarberry, and elm being the most commonly infected. Ash, beech, cherry, dogwood, sweet gum, hickory, maple, Osage-orange, persimmon, sassafras, walnut, sycamore, and willow also may be infected. It has been reported on 110 different species of trees in the eastern United States.